DISEASES

Disease-gene associations mined from literature

Literature associating FAM83A and amelogenesis imperfecta type 3A

FAM83A [ENSP00000428876]

Tumor-specific gene expressed in prostate protein; Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation; Belongs to the FAM83 family.

Synonyms:  FAM83A,  FAM83Ap,  hFAM83A,  Q86UY5,  Q86UY5p ...

Linkouts:  STRING  Pharos  UniProt