Literature associating FAM83A and amelogenesis imperfecta type 3A
Tumor-specific gene expressed in prostate protein; Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation; Belongs to the FAM83 family.
Synonyms: FAM83A, FAM83Ap, hFAM83A, Q86UY5, Q86UY5p ...