DISEASES

Disease-gene associations mined from literature

Literature associating MPP2 and familial melanoma

MPP2 [ENSP00000428182]

Membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2); Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells.

Synonyms:  MPP2,  MPP2p,  hMPP2,  B4DZ84,  D3DX48 ...

Linkouts:  STRING  Pharos  UniProt