DISEASES

Disease-gene associations mined from literature

Literature associating FYB and thrombocytopenia

FYB [ENSP00000427114]

Adhesion and degranulation promoting adaptor protein; Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

Synonyms:  FYB,  D6RAE8,  D6RC38,  D6RER7,  D6RFJ5 ...

Linkouts:  STRING  Pharos  UniProt