Literature associating PROM1 and infratentorial cancer
Prominin-like protein 1; May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner; CD molecules
Synonyms: PROM1, PROM1p, hPROM1, D6RBI0, D6RIF3 ...