DISEASES

Disease-gene associations mined from literature

Literature associating TNIP3 and inflammatory bowel disease 2

TNIP3 [ENSP00000426613]

A20-binding inhibitor of NF-kappa-B activation 3; Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Synonyms:  TNIP3,  TNIP3p,  hTNIP3,  H0Y9J7,  Q96KP6 ...

Linkouts:  STRING  Pharos  UniProt