Literature associating MCIDAS and cataract 18
Multiciliate differentiation and DNA synthesis associated cell cycle protein; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1; Belongs to the geminin family.
Synonyms: MCIDAS, D6RGH6, I6L8E2, D6RGH6p, hD6RGH6 ...