DISEASES

Disease-gene associations mined from literature

Literature associating MCIDAS and nosophobia

MCIDAS [ENSP00000426359]

Multiciliate differentiation and DNA synthesis associated cell cycle protein; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1; Belongs to the geminin family.

Synonyms:  MCIDAS,  D6RGH6,  I6L8E2,  D6RGH6p,  hD6RGH6 ...

Linkouts:  STRING  Pharos  UniProt