DISEASES

Disease-gene associations mined from literature

Literature associating MIB2 and left ventricular noncompaction

MIB2 [ENSP00000426103]

Zinc finger ZZ type with ankyrin repeat domain protein 1; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors; Ankyrin repeat domain containing

Synonyms:  MIB2,  MIB2p,  hMIB2,  D6R9Q6,  D6RAZ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM