Disease-gene associations mined from literature

Literature associating ATG12 and mouth disease

ATG12 [ENSP00000425107]

Autophagy-related protein 12; Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.

Synonyms:  ATG12,  ATG12p,  hATG12,  C1IDX9,  D6RB14 ...

Linkouts:  STRING  Pharos  UniProt  OMIM