Disease-gene associations mined from literature

Literature associating TENM3 and autosomal recessive spinocerebellar ataxia 12

TENM3 [ENSP00000424226]

Teneurin transmembrane protein 3; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer (By similarity).

Synonyms:  TENM3,  TENM3p,  hTENM3,  D6RGC5,  G3CAS9 ...

Linkouts:  STRING  Pharos  UniProt