Literature associating KLHL2 and parasitic protozoa infectious disease
Actin-binding protein Mayven; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors; BTB domain containing
Synonyms: KLHL2, KLHL2p, hKLHL2, B4DFZ5, D6R9G5 ...