DISEASES

Disease-gene associations mined from literature

Literature associating LARP7 and Pitt-Hopkins syndrome

LARP7 [ENSP00000422626]

La ribonucleoprotein domain family, member 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation; La ribonucleoprotein domain containing

Synonyms:  LARP7,  LARP7p,  hLARP7,  A0A024RDH5,  D6R9Z6 ...

Linkouts:  STRING  Pharos  UniProt