DISEASES

Disease-gene associations mined from literature

Literature associating ADAMTS12 and intrahepatic cholestasis of pregnancy

ADAMTS12 [ENSP00000422554]

A disintegrin and metalloproteinase with thrombospondin motifs 12; Metalloprotease that may play a role in the degradation of COMP. Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties; ADAM metallopeptidases with thrombospondin type 1 motif

Synonyms:  ADAMTS12,  D6REX0,  P58397,  D6REX0p,  hD6REX0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM