Literature associating FNIP1 and familial renal papillary carcinoma
FNIP1 [ENSP00000421985]
Folliculin-interacting protein 1; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. Competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins . May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways . May regulate phosphorylation of RPS6KB1 . ; Belongs to the FNIP family.
Synonyms: FNIP1, FNIP1p, hFNIP1, A0A087WX11, J3KNG8 ...