Literature associating KCNIP2 and congenital myasthenic syndrome 5
Cardiac voltage-gated potassium channel modulatory subunit; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity); EF-hand domain containing
Synonyms: KCNIP2, KCNIP2p, hKCNIP2, A6NFF4, Q3YAC7 ...