DISEASES

Disease-gene associations mined from literature

Literature associating PTK7 and neural tube defect

PTK7 [ENSP00000418754]

Inactive tyrosine-protein kinase 7; Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis; I-set domain containing

Synonyms:  PTK7,  PTK7p,  hPTK7,  C9J9E8,  C9JQR6 ...

Linkouts:  STRING  Pharos  UniProt