Disease-gene associations mined from literature

Literature associating MME and liver lymphoma

MME [ENSP00000418525]

Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 . Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers . ECO:0000269|PubMed:17101991, ECO:0000269|PubMed:20876573, ECO:0000269|PubMed:2531377, ECO:0000269|PubMed:27588448,; Belongs to the peptidase M13 family.

Synonyms:  MME,  A0A087WWM7,  C9IYX7,  C9J7X4,  C9J9X7 ...

Linkouts:  STRING  Pharos  UniProt