DISEASES

Disease-gene associations mined from literature

Literature associating DCUN1D2 and optic nerve sheath meningioma

DCUN1D2 [ENSP00000417706]

DCN1, defective in cullin neddylation 1, domain containing 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8- conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Synonyms:  DCUN1D2,  DCUN1D2p,  hDCUN1D2,  C9J2J1,  C9JAV2 ...

Linkouts:  STRING  Pharos  UniProt