Disease-gene associations mined from literature

Literature associating HS3ST6 and overhydrated hereditary stomatocytosis

HS3ST6 [ENSP00000416741]

Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3- OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate; Sulfotransferases, membrane bound

Synonyms:  HS3ST6,  HS3ST6p,  hHS3ST6,  J3KR40,  HS3ST5 ...

Linkouts:  STRING  Pharos