DISEASES

Disease-gene associations mined from literature

Literature associating FDXR and autosomal recessive disease

FDXR [ENSP00000416515]

NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver; Belongs to the ferredoxin--NADP reductase type 1 family.

Synonyms:  FDXR,  J3KRG8,  J3KS64,  J3QSF9,  P22570 ...

Linkouts:  STRING  Pharos  UniProt