Disease-gene associations mined from literature

Literature associating SERPINA1 and liver sarcoma

SERPINA1 [ENSP00000416066]

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin; Belongs to the serpin family.

Synonyms:  SERPINA1,  A6YP93,  E9KL23,  P01009,  Q3I0J7 ...

Linkouts:  STRING  Pharos  UniProt