Literature associating SERPINA1 and factor VIII deficiency
Short peptide from AAT; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin; Belongs to the serpin family.
Synonyms: SERPINA1, A0A0B4J278, E9KL23, G3V2B9, G3V387 ...