Disease-gene associations mined from literature

Literature associating INPP5K and Parkinson's disease 20

INPP5K [ENSP00000413937]

Skeletal muscle and kidney-enriched inositol phosphatase; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (By similarity).

Synonyms:  INPP5K,  INPP5Kp,  hINPP5K,  B7Z4V9,  C9JQW8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM