Literature associating TOP2A and frontal lobe neoplasm
DNA topoisomerase II, alpha isozyme; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity); Topoisomerases
Synonyms: TOP2A, TOP2Ap, hTOP2A, J3KTB7, J3QR57 ...