DISEASES

Disease-gene associations mined from literature

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Literature associating BCL7B and dermatitis

BCL7B [ENSP00000411073]

B-cell CLL/lymphoma 7 protein family member B; Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 . Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation . May play a role in lung tumor development or progression (By similarity). ; Belongs to the BCL7 family.

Synonyms:  BCL7B,  BCL7Bp,  hBCL7B,  F2Z3H6,  F8WDZ4 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.