Literature associating HERPUD1 and phacolytic glaucoma
Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway.
Synonyms: HERPUD1, HERPUD1p, hHERPUD1, B4DXX2, B4E3N8 ...