DISEASES

Disease-gene associations mined from literature

Literature associating CLDN4 and gastric adenocarcinoma

CLDN4 [ENSP00000409544]

Williams-Beuren syndrome chromosomal region 8 protein; Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Synonyms:  CLDN4,  CLDN4p,  hCLDN4,  B3KW38,  O14493 ...

Linkouts:  STRING  Pharos  UniProt