Literature associating CLDN4 and inflammatory bowel disease 20
Williams-Beuren syndrome chromosomal region 8 protein; Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Synonyms: CLDN4, CLDN4p, hCLDN4, B3KW38, O14493 ...