Literature associating TBRG1 and postural orthostatic tachycardia syndrome
Transforming growth factor beta regulator 1; Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability; Belongs to the TBRG1 family.
Synonyms: TBRG1, TBRG1p, hTBRG1, E9PI10, E9PK87 ...