DISEASES

Disease-gene associations mined from literature

Literature associating HDAC9 and hematologic cancer

HDAC9 [ENSP00000408617]

MEF2-interacting transcription repressor MITR; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription; Belongs to the histone deacetylase family. HD type 2 subfamily.

Synonyms:  HDAC9,  HDAC9p,  hHDAC9,  B5MCF1,  B7Z3P7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM