Disease-gene associations mined from literature

Literature associating CYTH2 and postpartum depression

CYTH2 [ENSP00000408236]

PH, SEC7 and coiled-coil domain-containing protein 2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth (By similarity); Pleckstrin homology domain containing

Synonyms:  CYTH2,  CYTH2p,  hCYTH2,  CYTH2-001,  CYTH2-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM