DISEASES

Disease-gene associations mined from literature

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Literature associating LAX1 and megacystis-microcolon-intestinal hypoperistalsis syndrome

LAX1 [ENSP00000406970]

Membrane-associated adapter protein LAX; Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells.

Synonyms:  LAX1,  LAX1p,  hLAX1,  Q8IWV1,  LAX ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.