Literature associating BRAP and astereognosia
RING-type E3 ubiquitin transferase BRAP2; Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport; Ring finger proteins
Synonyms: BRAP, BRAP-001, BRAP-002, BRAP-003, J3KNN7 ...