DISEASES

Disease-gene associations mined from literature

Literature associating MXD3 and myxosarcoma

MXD3 [ENSP00000401867]

Max-interacting transcriptional repressor MAD3; Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity); Basic helix-loop-helix proteins

Synonyms:  MXD3,  MXD3p,  hMXD3,  A0A024R7S0,  B4E0J1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM