DISEASES

Disease-gene associations mined from literature

Literature associating DNAH1 and infertility

DNAH1 [ENSP00000401514]

Axonemal beta dynein heavy chain 1; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme; Belongs to the dynein heavy chain family.

Synonyms:  DNAH1,  DNAH1p,  hDNAH1,  Q9P2D7,  DHC7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM