Literature associating TIA1 and frontotemporal dementia
TIA1 cytotoxic granule-associated RNA binding protein; Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
Synonyms: TIA1, TIA1p, hTIA1, C9JTN7, E5RG67 ...