Disease-gene associations mined from literature

Literature associating TIA1 and reticulosarcoma

TIA1 [ENSP00000401371]

TIA1 cytotoxic granule-associated RNA binding protein; Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Synonyms:  TIA1,  TIA1p,  hTIA1,  C9JTN7,  E5RG67 ...

Linkouts:  STRING  Pharos  UniProt  OMIM