DISEASES

Disease-gene associations mined from literature

Literature associating ERAP2 and eclampsia

ERAP2 [ENSP00000400376]

Leukocyte-derived arginine aminopeptidase; Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys; Aminopeptidases

Synonyms:  ERAP2,  ERAP2p,  hERAP2,  D6RF46,  D6RGW0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM