Literature associating HMGA1 and Pelizaeus-Merzbacher disease
High mobility group protein HMG-I/HMG-Y; HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions; Canonical high mobility group
Synonyms: HMGA1, HMGA1p, hHMGA1, P17096, Q5T6U8 ...