DISEASES

Disease-gene associations mined from literature

Literature associating CHRM2 and neurogenic bladder

CHRM2 [ENSP00000399745]

Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol; Cholinergic receptors muscarinic

Synonyms:  CHRM2,  CHRM2p,  hCHRM2,  A4D1Q0,  P08172 ...

Linkouts:  STRING  Pharos  UniProt