DISEASES

Disease-gene associations mined from literature

Literature associating ATF7 and familial atrial fibrillation

ATF7 [ENSP00000399465]

Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family; Basic leucine zipper proteins

Synonyms:  ATF7,  ATF7p,  hATF7,  K7ESA4,  P17544 ...

Linkouts:  STRING  Pharos  UniProt