Disease-gene associations mined from literature

Literature associating DDOST and autosomal recessive chronic granulomatous disease cytochrome b-positive type II

DDOST [ENSP00000399457]

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation; Glutamine amidotransferase like class 1 domain containing

Synonyms:  DDOST,  P39656,  U3KQ84,  KIAA0115,  OK/SW-cl.45 ...

Linkouts:  STRING  Pharos  UniProt