DISEASES

Disease-gene associations mined from literature

Literature associating RGS4 and bipolar disorder

RGS4 [ENSP00000397181]

Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

Synonyms:  RGS4,  RGS4p,  hRGS4,  A0A024R909,  E9PR32 ...

Linkouts:  STRING  Pharos  UniProt  OMIM