DISEASES

Disease-gene associations mined from literature

Literature associating SFTPA1 and lung disease

SFTPA1 [ENSP00000397082]

35 kDa pulmonary surfactant-associated protein; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity); Belongs to the SFTPA family.

Synonyms:  SFTPA1,  SFTPA1p,  hSFTPA1,  A0A024QZP2,  B4DNR9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM