Literature associating FGD4 and Charcot-Marie-Tooth disease
FYVE, RhoGEF and PH domain-containing protein 4; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8 (By similarity); Pleckstrin homology domain containing
Synonyms: FGD4, FGD4p, hFGD4, B7Z493, E9PJX4 ...