Literature associating KCNK2 and autosomal recessive limb-girdle muscular dystrophy type 2X
Outward rectifying potassium channel protein TREK-1; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage- dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1 (By similarity); Potassium two pore domain channel subfamily K
Synonyms: KCNK2, KCNK2p, hKCNK2, B4DGU6, C9JDK1 ...