Disease-gene associations mined from literature

Literature associating NFATC1 and bone remodeling disease

NFATC1 [ENSP00000389377]

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity); Nuclear factors of activated T-cells

Synonyms:  NFATC1,  NFATC1p,  hNFATC1,  F5H4S8,  K7EQ04 ...

Linkouts:  STRING  Pharos  UniProt