Disease-gene associations mined from literature

Literature associating DCC and scoliosis

DCC [ENSP00000389140]

Immunoglobulin superfamily DCC subclass member 1; Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene; Fibronectin type III domain containing

Synonyms:  J3QKL2,  J3QLB0,  J3QQJ6,  J3QS93,  P43146 ...

Linkouts:  STRING  Pharos  UniProt  OMIM