DISEASES

Disease-gene associations mined from literature

Literature associating CTU2 and renal agenesis

CTU2 [ENSP00000388320]

Cytosolic thiouridylase subunit 2 homolog (S. pombe); Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Synonyms:  CTU2,  CTU2p,  hCTU2,  B4DS10,  H3BNM3 ...

Linkouts:  STRING  Pharos  UniProt