Literature associating AGBL3 and CREST syndrome
ATP/GTP binding protein-like 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin; M14 carboxypeptidases
Synonyms: AGBL3, AGBL3p, hAGBL3, F8W6Y5, F8W7R4 ...