Disease-gene associations mined from literature

Literature associating AGBL3 and CREST syndrome

AGBL3 [ENSP00000388275]

ATP/GTP binding protein-like 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin; M14 carboxypeptidases

Synonyms:  AGBL3,  AGBL3p,  hAGBL3,  F8W6Y5,  F8W7R4 ...

Linkouts:  STRING  Pharos  UniProt